ActivSignal Email Format
Biotechnology ResearchMassachusetts, United States2-10 Employees
BlueSCAI™: Harness the Power of Ultra-Sensitive Protein Profiling in Multiplex Unlock Critical Protein Biomarkers with Unprecedented Detection and Quantitation with Best-In-Class Platform. Down to attomolar sensitivity Ultra-sensitive for detecting the lowest abundance biomarkers. 5 Logs LOD Advantage Up to 5 logs LOD advantage over leading multiplex proteomics platforms, head-to-head comparison. BlueSCAI Background Removal Detects down to <1,000 molecules per target per well, using the same antibody pairs as commercial ELISAs. Locked-in Specificity Paired-antibody proximity detection with NGS read-out of ligated DNA barcodes ensures high specificity. Mechanistic Biology Biologic perturbation mapping. Map time-resolved pathway responses to stimuli, drugs, and stressors—at high plex, from tiny samples. Broad Dynamic Range Measure changes across the biological spectrum. Tunable for optimal NGS read-out. Multiplex Biomarker Quantification ActivSignal's BlueSCAI is built on our patented Multiplex Paired-Antibody Amplified Detection (MPAD) technology — a highly specific and sensitive platform for profiling proteins and their modifications in multiplex. BlueSCAI (Background lowering using Serial Capture, Adapter Insertion) detects protein targets using specific, dual-binding of antibody-pairs, an architecture that increases specificity, an integrated capture-release-recapture mechanism that dramatically lowers background, signal amplification, and specific NGS read-out — with a large and tunable dynamic range. Highly scalable — from single to tens to hundreds of biomarkers, measured in multiplex from the same small sample with high specificity and sensitivity. Earlier Detection of Pancreatic Cancer The PanDx™ assay read-out from the patient sample, across the multiple proteins and other biomarkers in the Panel, provides a "bio-signature" for that individual. for the detection of early-stage cancer. Visit our website for more details.