Advanced NanoTherapies

Medical Equipment ManufacturingCalifornia, United States11-50 Employees

Advanced NanoTherapies develops a functionalized nanoparticle platform for local, dual-drug delivery during catheter-based interventions. SirPlux Duo is the first drug-coated balloon to deliver sirolimus and paclitaxel simultaneously through a single device, enabling controlled cellular uptake and sustained tissue retention at the lesion site.

The technology is exclusively licensed from Cleveland Clinic and has received FDA Breakthrough Designation. ANT is advancing toward U.S. pivotal execution across coronary and peripheral vascular disease, with programs in in-stent restenosis, small-vessel coronary intervention, and below-the-knee peripheral artery disease.

Advanced NanoTherapies is a T45 Labs portfolio company.
SirPlux Duo is an investigational device and has not yet been approved for commercial use.

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