Advanced NanoTherapies
Medical Equipment ManufacturingCalifornia, United States11-50 Employees
Advanced NanoTherapies develops a functionalized nanoparticle platform designed to enable local dual-drug delivery during catheter-based interventions. Its lead program, SirPlux Duo, is a drug-coated balloon capable of delivering sirolimus and paclitaxel simultaneously from a single device, with the goal of controlled cellular uptake and sustained tissue retention at the treatment site. The technology is exclusively licensed from Cleveland Clinic and has received FDA Breakthrough Designation. The company operates in medical equipment manufacturing, focusing on coronary and peripheral vascular disease with development work in in-stent restenosis, small-vessel coronary intervention, and below-the-knee peripheral artery disease. Based in Santa Clara, California, the organization is advancing toward pivotal U.S. trials for SirPlux Duo, which remains investigational and not approved for commercial use, and is led by CEO Marwan Berrada-Sounni and Medical Director Dr. Azeem Latib.