ALine, Inc.

Biotechnology ResearchCalifornia, United States11-50 Employees

Experts in the Science and Engineering of Microfluidics for the Life Science and Medical Device Markets. Successful commercialization Providing Engineering, Custom Fabrication, and Volume Production. ALine’s scientific expertise in the physics of Microfluidics, and in bioanalytical systems enables practical, product oriented solutions for integrating complex analytical assays into engineered products. We integrate modular fluidic & instrument components to create a scalable, repeatable, and, if required, a semi-automated analytical system for both active and passive microfluidic control. ISO9001:2008; ISO13485 compliant In house capabilities: laser cutting , lamination, thermal press 3D printing machining Injection molding design Microfluidic Design, Engineering and Production: - Rapid batch production of microfluidics in standard materials with modular designs. - “Smart Capping Layer”: • Reduce injection molded part complexity • Achieve robust performance with a shorter development cycle - Designs for manufacture starts at program initiation - Manufacture and Assembly for volume production - Robust, functional solutions for fluid control in the chip; passive & active - Design and Integration of injection molded component - Sensor integration – optical or electrochemical - Reagent integration (blister packs, dried reagents) - Materials selection and verification expertise Instrumented Control of Microfluidic Devices: - Modular & Custom Instrumentation with Pneumatic, Flow, and Thermal Control - Focus on assay optimization with repeatable experimental control - Reduce risk and cost of system integration Applications • Immunoassays, IVDs • Cell Culture; Organ-on-Chip • Nucleic Acid Detection • Multiplexed Fluid Control Manifolds • Flow Cells for Array Based Detection • Flow cells for Electroactive detection • Flow cells for Optical Detection • Droplet-based Microfluidics

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