Alios BioPharma
Biotechnology ResearchCalifornia, United States11-50 Employees
Alios BioPharma is a clinical-stage biotechnology company based in South San Francisco, California, focused on developing antiviral therapies for respiratory diseases. Its discovery platform leverages a proprietary antiviral candidate library and virology-based screening systems to identify compounds that inhibit viral replication. The lead candidate, AL-8176, is an oral anti-RSV agent in Phase 2a trials designed to block RSV replication by targeting the viral polymerase. Early data show potent activity across RSV strains in vitro and favorable tolerability in initial studies, with Phase 1 completed and no serious adverse events or discontinuations. Founded in 2008, the company was acquired by Johnson & Johnson in 2014 and continues to pursue preclinical programs targeting influenza, rhinovirus, and RSV.