Avelas Biosciences, Inc. Email Format
Biotechnology ResearchCalifornia, United States2-10 Employees
Avelas Biosciences is a clinical-stage biotechnology company focused on fluorescence imaging to enable real-time cancer detection during surgery. Its lead agent, pegloprastide (AVB-620), is designed to be used with a fluorescence camera system to help visualize cancer during operative procedures and improve surgical precision. The technology utilizes Activatable Cell Penetrating Peptide (ACPP) delivery to target tumors through their biochemistry, a foundation traced to the lab of Nobel Prize laureate Dr. Roger Y. Tsien at UC San Diego. Based in La Jolla, California, the company operates in the biotechnology research sector and targets oncologic surgery where real-time visualization could affect outcomes. In a prospective study of breast-conserving surgery for primary breast cancer, pegloprastide correctly identified cancer in up to 75% of women with positive margins who would otherwise have required a reoperation, and the company is pursuing additional cancer types such as ovarian, colorectal, head and neck, melanoma, and sarcoma.