Cabaletta Bio
Biotechnology ResearchPennsylvania, United States51-200 Employees
Cabaletta Bio is a mid-sized biotechnology company focused on developing engineered T cell therapies for autoimmune diseases. The company pursues two platforms: CARTA, which uses CD19-targeted CAR T cells, and CAART, which employs chimeric autoantibody receptor T cells. Its lead CARTA candidate, CABA-201, is a CD19 CAR T cell with a 4-1BB co-stimulatory domain being evaluated in systemic lupus erythematosus and myositis, while CAART candidates include DSG3-CAART for mucosal pemphigus vulgaris and MuSK-CAART for MuSK myasthenia gravis. The company operates in the biotechnology research industry and is headquartered in Philadelphia, Pennsylvania. In April 2026, Cabaletta Bio announced a 10-year commercial supply agreement with Cellares, expanding a prior collaboration and highlighting ongoing manufacturing development. It trades on Nasdaq under the ticker CABA.