Exicure Email Format

Biotechnology ResearchIllinois, United States2-10 Employees

Exicure, Inc. is a biotechnology research company developing nucleic acid therapies designed to target RNA in validated disease pathways, focusing on neurological disorders and hair loss. Based in Chicago, Illinois, it operates its discovery and development activities from a dedicated in-house facility that spans about 30,000 square feet and supports rapid synthesis and screening of oligonucleotides. The company emphasizes in vitro and in vivo models to assess potency, uptake, and duration of effect, reflecting its objective of advancing RNA-targeted therapeutics. Its lead program pursues a non-opioid analgesic directed at the Nav1.7 channel (SCN9A), with additional candidate molecules identified across central nervous system conditions such as Huntington disease, Angelman syndrome, Batten disease, spinocerebellar ataxia, and sporadic amyotrophic lateral sclerosis. Exicure announced a co-development collaboration with Adbiotech to explore combination therapies based on Burixafor (GPC-100) across multiple therapeutic areas. The firm operates within the biotechnology research sector, seeking to enable new treatment options through its RNA-targeting platform and in-house discovery capabilities.

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