Flare Therapeutics Email Format
Biotechnology ResearchMassachusetts, United States51-200 Employees
Flare Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, focused on developing precision medicines for oncology and other therapeutic areas. It aims to drug transcription factors, a previously undruggable target class, using an integrated discovery platform to identify validated ligands for the undrugged proteome. Its lead program, FX-909, is an oral, first-in-class inhibitor of PPARG for locally advanced or metastatic urothelial cancer, with clinical proof-of-concept in early trials and ongoing Phase 1B dosing. Its FX-111 program is a novel degrader targeting ARON, the transcriptionally active, hormone-bound androgen receptor. In 2026, Flare Therapeutics announced it would present three posters at the AACR Annual Meeting 2026, reflecting ongoing clinical activity.