Forge Therapeutics, Inc.
Biotechnology ResearchCalifornia, United States11-50 Employees
Forge Therapeutics is a San Diego, California-based biotechnology company that develops novel medicines by combining bio-inorganic chemistry with medicinal chemistry to target metalloproteins. Its approach centers on the metal at an enzyme's active site to guide the discovery of metalloprotein inhibitors, a strategy used to identify new classes of therapeutic candidates. The company has focused on anti-infective programs, pursuing partnerships to advance antibiotic candidates through early development toward the clinic. It operates with a small to mid-sized team in the biotechnology research sector and has established partnerships with Roche and Basilea Pharmaceutica to discover, develop, and commercialize novel antibiotics. In 2023, the company merged with Blacksmith Medicines, a development that signals a notable change in its corporate trajectory within the San Diego biotech ecosystem.