Jaguar Gene Therapy

Biotechnology ResearchIllinois, United States11-50 Employees

Jaguar Gene Therapy is a biotechnology company focused on advancing gene therapy for patients with severe genetic diseases, including conditions that affect sizeable patient populations. Based in Lake Forest, Illinois, the team brings together expertise in chemistry, manufacturing and controls, regulatory, clinical, and commercial development to move therapies toward patients with a focus on safety and product purity.

Its initial pipeline includes JAG101 for Type 1 galactosemia, JAG301 for Type 1 diabetes, and a SHANK3-related neurodevelopmental disorder associated with Phelan-McDermid syndrome. The company seeks opportunities to broaden its portfolio through collaborations with academic institutions. In December 2025, Andelyn Biosciences partnered with Jaguar Gene Therapy to perform late-stage process performance qualification manufacturing of JAG201 for PMS caused by SHANK3 haploinsufficiency.

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