Madrigal Pharmaceuticals
Pharmaceutical ManufacturingPennsylvania, United States1001-5000 Employees
Madrigal Pharmaceuticals is a biopharmaceutical company focused on developing therapies for metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease previously known as NASH. Its aim is to halt or reverse liver fibrosis and resolve MASH to prevent progression to cirrhosis, liver failure, and related complications. Based in Conshohocken, Pennsylvania, the company operates within the pharmaceutical manufacturing sector and maintains a sizable workforce. In 2026, Madrigal presented new data at the EASL Congress supporting Rezdiffra as a foundational therapy for MASH. The company also entered into an exclusive global license with Arrowhead Pharmaceuticals to develop, manufacture, and commercialize ARO-PNPLA3, a program designed to silence PNPLA3 expression in hepatocytes.