Manifold Bio Employee Directory
Biotechnology ResearchMassachusetts, United States51-200 Employees
Manifold Bio is a biotechnology research company based in Boston, Massachusetts, pursuing an AI-guided discovery platform for direct-to-in vivo protein design. Its computational design engine combines AI-guided protein design with multiplexed in vivo data, creating an iterative cycle that links discovery to translation toward organism-scale biology. The company maintains an internal pipeline of novel therapeutics and collaborates with leading pharmaceutical partners to accelerate the path from biology to clinical impact. In the biopharmaceutical landscape, Manifold Bio positions itself as a platform therapeutics company that seeks to translate organism-scale biology into clinically meaningful therapies through collaborations and translation-focused work. A notable recent development is a strategic collaboration with Roche announced in November 2025 to develop blood-brain barrier shuttles for multiple neurological diseases.