Mateon Therapeutics
Biotechnology ResearchCalifornia, United States11-50 Employees
Mateon Therapeutics is a biotechnology research company that focuses on vascular targeted therapy for orphan oncology indications. It develops two complementary approaches—vascular disrupting agents that target existing tumor vessels, and anti-angiogenic agents that suppress the growth of new vessels. The company explores combining these strategies to disrupt tumor vasculature and prevent new blood vessel formation, with the aim of improving cancer treatment. The organization leverages its intellectual property portfolio and product development expertise to advance vascular targeted therapy. The company is based in South San Francisco, California, operating within the biotechnology research sector focused on oncology therapies. In 2023, Mateon launched a study of OT-101, a TGF-β2 inhibitor, in combination with pembrolizumab for malignant pleural mesothelioma.