Olema Oncology
Biotechnology ResearchCalifornia, United States51-200 Employees
Olema Oncology is a San Francisco-based biotechnology company focused on developing cancer therapies with an emphasis on breast cancer. Its lead program, palazestrant (OP-1250), is an oral complete estrogen receptor antagonist in development for metastatic breast cancer, and its pipeline includes OP-3136, a potent, oral inhibitor of the KAT6 pathway. In May 2026, Olema announced a clinical trial collaboration with Bayer, reflecting active partnerships to advance its programs. The company has progressed OP-3136 into a Phase 1 clinical study and disclosed initial data through a poster presentation at the ASCO Annual Meeting. Olema states it operates with a focused team supported by leadership and advisers to advance its mission.