Retrotope, Inc.
Pharmaceutical ManufacturingCalifornia, United States11-50 Employees
Retrotope, Inc. is a private pharmaceutical company based in Los Altos, California, focused on developing therapies for degenerative diseases. Its lead candidate, RT001, aims to protect cells from oxidative stress by slowing lipid peroxidation in mitochondrial membranes, supporting mitochondrial function in energy-demanding tissues such as the brain, retina, and heart. The compound is designed to resemble ordinary fats so it distributes through tissues as needed. In human trials, RT001 demonstrated safety in a Phase 1/2 study in Friedreich's ataxia. The company has built a network of more than 50 collaborations with major centers worldwide to advance its understanding of disease mechanisms. In October 2021, Retrotope reported positive preclinical data for RT011 at the Dry AMD Therapeutic Development Summit.