Saint Francis Health System

Hospitals and Health CareOklahoma, United States1001-5000 Employees

Saint Francis Health System is a Catholic, not-for-profit health network based in Tulsa, Oklahoma, delivering care across eastern Oklahoma. Anchored by Saint Francis Hospital, the largest hospital in Oklahoma, the system operates a network of specialty centers and more than 100 outpatient locations through Warren Clinic, including the region’s only children’s hospital.

Founded in 1960 by Natalie O. and William K. Warren Sr., it provides a full continuum of care spanning primary care through advanced specialties, such as heart and vascular services, cancer care, behavioral health, and women’s and children’s health. The organization is described as the largest private employer in eastern Oklahoma, with a substantial workforce serving communities in and around Tulsa. In 2026, Saint Francis expanded its network by acquiring the MedWise Urgent Care centers and integrating them into its operations.

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