Seal Rock Therapeutics
Biotechnology ResearchWashington, United States2-10 Employees
Seal Rock Therapeutics is a clinical-stage biotechnology company focused on developing therapeutics for diseases with high unmet medical need. Its lead program targets the ASK1 pathway and, in combination with LRRK2/ASK1 signaling, aims to modulate neurodegenerative and inflammatory processes in conditions such as Parkinson's disease and ALS; additional development efforts include oral SRT-015 for liver diseases and potential applications in cardiac and immunological indications. The company positions itself in the biotechnology research industry by pursuing disease-modifying agents that intervene in multiple causal pathways and disrupt detrimental feedback loops, with several programs advancing in preclinical development. Based in Seattle, Washington, Seal Rock Therapeutics operates on a small team and has engaged in a recent collaboration with GENFIT to develop an injectable formulation of SRT-015 for acute liver disease, including Acute-on-Chronic Liver Failure (ACLF).