Signature Medical Group Email Format

Hospitals and Health CareMissouri, United States51-200 Employees

Signature Medical Group is a private, mid-sized, multi-specialty medical group that operates within the hospitals and health care sector, with a substantial footprint in Missouri and Kansas. Based in the St. Louis area, the organization was founded in 2001 when physicians formed what became the largest orthopedic physician group in the city. Over time it has grown into one of the region’s largest private multi-specialty networks, reflecting a broad scope of clinical services. The group has been recognized for workplace quality, being named a 2024 Best Places to Work Finalist by the St. Louis Business Journal.

Its physician network delivers specialty medical care to patients across multiple disciplines in Missouri and Kansas, with a historical emphasis on orthopedic care. Peer recognition has included Top Doctors honors for 11 Signature Medical Group physicians in 2024 and 12 in 2025, underscoring the credibility of its clinician team.

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