Insights

Strategic Partnerships Synthekine has a global collaboration with Sanofi to develop IL-10 receptor agonists for inflammatory diseases, indicating openness to co-development and large-scale pharma partnerships that could be expanded to additional targets or regions.

Clinical Momentum Recent SITC 2025 activity with PD-L1 negative programs and initial clinical data on STK-012 plus pembrolizumab suggests a momentum in oncology combos that could be leveraged to identify co-development or licensing opportunities with manufacturers of checkpoint inhibitors.

Productive Leadership Key recent executive hires in 2024, including chief development officer and chief business officer, signal a strengthened commercial and development focus that can accelerate partner negotiations and deal structuring.

Cytokine Platform Investment in cytokine partial agonism and immunological specificity offers an attractive differentiation for partners seeking safer, efficacious immunotherapies, presenting opportunities for co-licensing or joint programs around new cytokine pathways.

Financially Viable With mid-market revenue and substantial funding runway, Synthekine presents a viable collaboration prospect for regional biotech partners and contract development organizations seeking to co-develop or sponsor early-to-mid stage programs.

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Synthekine Tech Stack

Synthekine uses 8 technology products and services including iCIMS, WordPress, OneTrust, and more. Explore Synthekine's tech stack below.

Media & News

Synthekine's Email Address Formats

Synthekine uses at least 3 email formats:
Synthekine Email FormatsExamplePercentage
FLast@synthekine.comJDoe@synthekine.com
98%
FMiddleLast@synthekine.comJMichaelDoe@synthekine.com
1%
FiLast@synthekine.comJoDoe@synthekine.com
1%

Frequently Asked Questions

What is Synthekine's official website and social media links?

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Synthekine's official website is synthekine.com and has social profiles on LinkedIn and Crunchbase.

How much revenue does Synthekine generate?

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As of August 2026, Synthekine's annual revenue is estimated to be $25M - $50M.

What is Synthekine's SIC code and NAICS code?

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Synthekine's SIC code is 8731 - Commercial Physical and Biological Research and NAICS code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology).

How many employees does Synthekine have currently?

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As of August 2026, Synthekine has approximately 56 employees across 1 continents, including North America. Key team members include Head Of It: A. B., Vice President, Translational & Bioanalytical Sciences: A. M. and Sr. Director, Program Management: H. Z. Explore Synthekine's employee directory with LeadIQ.

What industry does Synthekine belong to?

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Synthekine operates in the Biotechnology Research industry.

What technology does Synthekine use?

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Synthekine's tech stack includes iCIMS, WordPress, OneTrust, Salesforce, Microsoft 365, DocuSign, KnowBe4 and Piwik PRO Core.

What is Synthekine's email format?

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Synthekine's email format typically follows the pattern of FLast@synthekine.com. Find more Synthekine email formats with LeadIQ.

How much funding has Synthekine raised to date?

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As of August 2026, Synthekine has raised $290M in funding. The last funding round occurred on Jan 06, 2023 for $100M.

When was Synthekine founded?

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Synthekine was founded in 2018.
Synthekine logo

Synthekine

Biotechnology ResearchCalifornia, United States51-200 Employees

Synthekine is a biotechnology research company based in Menlo Park, California, at 1505 Obrien Drive Suite a, with 51-200 employees. The company develops engineered cytokine therapeutics for cancer and autoimmune diseases, applying immunological insights to guide targeted protein engineering, including partial agonism and immunological specificity to balance safety and efficacy. Its lead programs have shown promising efficacy and tolerability in preclinical studies, and it is pursuing additional cytokine partial agonists that selectively modulate key immune pathways. In 2025, Synthekine announced a PD-L1-negative program at the SITC annual meeting and presented initial clinical data for STK-012 in combination with pembrolizumab and chemotherapy in first-line, PD-L1-negative nonsquamous NSCLC. The company has established a worldwide collaboration with Sanofi to develop IL-10 receptor agonists for inflammatory diseases and has programs such as STK-026, an IL-12 partial agonist, and STK-009 plus SYNCAR-001, a CD19 CAR-T combination therapy.

Section iconCompany Overview

SIC Code
8731 - Commercial Physical and Biological Research
NAICS Code
541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Founded
2018
Employees
51-200

Section iconFunding & Financials

  • $290M

    Synthekine has raised a total of $290M of funding over 3 rounds. Their latest funding round was raised on Jan 06, 2023 in the amount of $100M as a Series C.

  • $25M - $50M

    Synthekine's revenue is estimated to be in the range of $25M - $50M

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