SyntheX

Biotechnology ResearchCalifornia, United States11-50 Employees

SyntheX is a biotechnology company focused on precision drug discovery through synthetic biology. It has developed a platform that combines engineered genetic circuits with intracellular selection to identify novel compounds with mechanisms outside traditional screening methods. The company specializes in targeting protein–protein interactions and developing molecular glues for targeted protein degradation, enabling binding to previously uncharacterized sites on protein targets. Based in San Francisco, California, the company supports an internal oncology program and engages in external collaborations. In October 2022, Bristol Myers Squibb announced a partnership with SyntheX to pursue molecular glue degrader discovery, reflecting the company's active role in the field.

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