SystImmune
Biotechnology ResearchWashington, United States51-200 Employees
Based in Redmond, Washington, SystImmune is a biotechnology company established in 2014 that concentrates on cancer therapeutics. It develops antibody-based treatments, including bispecific and trispecific antibodies as well as antibody-drug conjugates, with the aim of modulating the solid tumor microenvironment to attack tumors directly or to mobilize the immune system. The organization draws on experienced immuno-oncology scientists and relies on multiple technology platforms to advance these therapies. Notably, iza-bren (izalontamab brengitecan) is being developed in partnership with Bristol Myers Squibb under a collaboration and exclusive license arrangement for territories outside China. The company has presented data from its clinical programs at major oncology meetings, including ASCO 2026 and ELCC 2026, highlighting progress across several antibody-drug conjugates and antibody candidates.