Insights

Clinical-stage Opportunity Trefoil Therapeutics is a clinical-stage biotechnology company focused on regenerative therapies for corneal diseases, presenting a potential long-term partnership window for ophthalmology stakeholders and contract development/clinical services organizations.

Lead Asset Focus The lead investigational medicine TTHX1114 targets corneal endothelial dystrophies and related conditions, suggesting opportunities to service imaging, biomarkers, regulatory consulting, and specialized manufacturing collaborations.

Small Team Advantage With 11-50 employees, Trefoil may benefit from streamlined vendor relationships, agile project management, and scalable CRO/CMO partnerships to accelerate development timelines and reduce internal overhead.

Funding & Growth Existing funding of about $90M and revenue in the low single digits indicate readiness for strategic partnerships, licensing discussions, or co-development deals to advance their clinical programs.

Ophthalmology Focus A proven leadership and scientific focus in ophthalmology, plus ARVO data presentations and Eyecelerator recognitions in the past, signals strong market positioning opportunities for specialized device, diagnostic, or translational collaboration.

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Trefoil Therapeutics Tech Stack

Trefoil Therapeutics uses 8 technology products and services including Amazon Web Services, Cloudflare, Wix, and more. Explore Trefoil Therapeutics's tech stack below.

Media & News

Trefoil Therapeutics's Email Address Formats

Trefoil Therapeutics uses at least 1 email format:
Trefoil Therapeutics Email FormatsExamplePercentage
FLast@trefoiltherapeutics.comJDoe@trefoiltherapeutics.com
100%

Frequently Asked Questions

What is Trefoil Therapeutics's official website and social media links?

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Trefoil Therapeutics's official website is trefoiltherapeutics.com and has social profiles on LinkedIn and Crunchbase.

How much revenue does Trefoil Therapeutics generate?

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As of August 2026, Trefoil Therapeutics's annual revenue is estimated to be $1M - $10M.

What is Trefoil Therapeutics's SIC code and NAICS code?

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Trefoil Therapeutics's SIC code is 8731 - Commercial Physical and Biological Research and NAICS code is 3254 - Pharmaceutical and Medicine Manufacturing.

How many employees does Trefoil Therapeutics have currently?

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As of August 2026, Trefoil Therapeutics has approximately 10 employees across 1 continents, including North America. Key team members include Co-Founder: K. T., Co-Founder: K. T. and Co Founder: M. B. Explore Trefoil Therapeutics's employee directory with LeadIQ.

What industry does Trefoil Therapeutics belong to?

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Trefoil Therapeutics operates in the Pharmaceutical Manufacturing industry.

What technology does Trefoil Therapeutics use?

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Trefoil Therapeutics's tech stack includes Amazon Web Services, Cloudflare, Wix, WordPress, Mailchimp, Microsoft 365, Zepto and Vimeo.

What is Trefoil Therapeutics's email format?

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Trefoil Therapeutics's email format typically follows the pattern of FLast@trefoiltherapeutics.com. Find more Trefoil Therapeutics email formats with LeadIQ.

How much funding has Trefoil Therapeutics raised to date?

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As of August 2026, Trefoil Therapeutics has raised $90M in funding. The last funding round occurred on May 06, 2025 for $4.6M.

When was Trefoil Therapeutics founded?

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Trefoil Therapeutics was founded in 2013.
Trefoil Therapeutics logo

Trefoil Therapeutics

Pharmaceutical ManufacturingCalifornia, United States2-10 Employees

Trefoil Therapeutics is a small to mid-sized biotechnology company focused on restoring sight for people with corneal diseases through regenerative therapies. Based in San Diego, California, the company operates in the pharmaceutical manufacturing sector and is currently clinical-stage. Its lead investigational medicine, TTHX1114, is being studied for corneal endothelial dystrophies and related conditions via intracameral injection, with potential to be first-in-class if successful. Its leadership comes from scientists with deep experience in ophthalmology, guiding work toward regenerative approaches for corneal diseases.

In 2023, Trefoil announced data presentations on TTHX1114 at the ARVO annual meeting.

Section iconCompany Overview

SIC Code
8731 - Commercial Physical and Biological Research
NAICS Code
3254 - Pharmaceutical and Medicine Manufacturing
Founded
2013
Employees
2-10

Section iconFunding & Financials

  • $90M

    Trefoil Therapeutics has raised a total of $90M of funding over 8 rounds. Their latest funding round was raised on May 06, 2025 in the amount of $4.6M as a Venture Round.

  • $1M - $10M

    Trefoil Therapeutics's revenue is estimated to be in the range of $1M - $10M

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