ZZ Biotech, LLC Email Format

BiotechnologyCalifornia, United States51-200 Employees

ZZ Biotech, LLC is a mid-sized biotechnology research company based in San Diego, founded in 2006. It focuses on developing biologic therapies for ischemic stroke and other neurological diseases, as well as wound healing applications such as diabetic foot ulcers, with its lead program 3K3A-APC as a next-generation variant of recombinant APC. 

The company has completed a multicenter Phase 2 trial in acute ischemic stroke to evaluate safety, tolerability, and activity of 3K3A-APC, including use after standard treatments like tPA and mechanical thrombectomy. The trial reported that all dose levels tested were safe and that treatment reduced bleeding complications associated with these procedures. ZZ Biotech has extended its intellectual property to cover APC-based wound healing and inflammatory skin conditions, and in 2020 announced FDA Fast Track designation for its stroke program.

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