A2A Pharmaceuticals Employee Directory

Pharmaceutical Manufacturing2-10 Employees

A2A Pharmaceuticals is a pharmaceutical manufacturing company focused on designing computationally optimized small molecule therapeutics for cancer and antibiotic-resistant bacterial infections. The company employs a small team, with 2 to 10 employees. Its oncology programs aim to inhibit essential protein-protein interactions implicated in leukemia and diverse solid tumors, interactions that drive cancer progression but are non-essential in normal cells. Its antibiotic programs target biosynthetic enzymes in gram-negative bacteria in pathways not found in humans, with targets selected to minimize resistance and to represent modalities not yet covered by clinically used therapeutics. The development approach relies on the proprietary SCULPT platform to design and evaluate large in silico libraries—thousands to millions of small molecules—through iterative rounds that total upwards of 100 million compounds, assessing potency and ADMET properties; in 2018 the company collaborated with Insilico Medicine and launched Consortium.AI to apply AI to drug discovery.

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