Altis Biosystems
Biotechnology ResearchNorth Carolina, United States11-50 Employees
Altis Biosystems operates in biotechnology research, providing human-relevant in vitro platforms derived from stem cells to support preclinical drug discovery. The company aims to reduce the need for animal testing by delivering tools and expertise that illuminate human biology. Its flagship RepliGut Planar models use donor intestinal stem cells to generate the essential cell types of the gastrointestinal epithelium for drug testing and development. Based in Durham, North Carolina, Altis serves pharmaceutical companies and life science researchers seeking safer, more predictive means to study intestinal biology, disease models, and compound screening. The RepliGut family is designed to address the limitations of traditional cell lines and animal models by offering a physiologically relevant human platform for evaluating toxicity, disposition, and efficacy. In January 2024 the company announced a collaboration with CN Bio to integrate its RepliGut Planar-Jejunum with CN Bio's liver-on-a-chip, creating a multi-organ system intended to mimic oral drug administration.