Gateway Down Syndrome Association
Non-profit OrganizationsMissouri, United States11-50 Employees
Gateway Down Syndrome Association is a nonprofit organization based in the St. Louis area that supports and celebrates people with Down syndrome and their families across all stages of life. It is described as the region’s longest-running, most comprehensive resource on Down syndrome and the only local organization offering support from prenatal stages through adulthood. Its mission centers on helping individuals with Down syndrome reach their full potential within the community. The organization is based in St. Louis and operates with a small to mid-sized staff, coordinating programs, events, and volunteer opportunities for families and supporters. In October 2025, it planned to host the SEMO Step Up for Down Syndrome event in Cape Girardeau, demonstrating its regional outreach beyond the city.