I-Mab Biopharma
Biotechnology ResearchMaryland, United States51-200 Employees
I-Mab Biopharma is a U.S.-based biotechnology company focused on precision immuno-oncology for cancer. Headquartered in Rockville, Maryland, the company operates in the biotechnology research sector and trades on NASDAQ as IMAB. Its lead program, givastomig, is a bispecific antibody designed to direct the immune system against Claudin 18.2-positive gastric cancers by engaging the 4-1BB co-stimulatory pathway in the tumor microenvironment. Givastomig is in early-phase clinical testing for first-line metastatic gastric cancer with potential applicability to other solid tumors. Early data suggest tumor-targeted T-cell activation with a potentially favorable safety profile, and in 2025 the company presented updated givastomig data at the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics conference.