Nostrum Biodiscovery
Biotechnology ResearchCatalonia, Spain11-50 Employees
Let's imagine a company that is able to speed up and increase the accuracy of the studies prior to the commercialization of pharmaceutical and biotech products. A young enterprise based on front line research, specialized in cutting-edge bioinformatics and ready to apply supercomputing power to the prediction of drug-target interactions and to the optimization of enzymes involved in biotechnological processes. A company devoted to solve issues related to drug discovery, precision medicine and industrial enzymology. Rethink and accelerate, that’s what NBD is about. We estimate that our approach can definitely reduce the early-stage drug development by up to two years and save around 15-20% in this first phase. Actually, this represents an estimated saving on average of 40 million Euros. Our core technologies include: PELE: The efficacy of PELE (Protein Energy Landscape Exploration) in predicting protein-ligand interactions was considered exceptional in the last Community Structure-Activity Resource (CSAR) carried out by the University of Michigan and GSK. ED/MD: Method to efficiently explore the flexibility of macromolecular targets and their use in rational drug design. MDWeb suite: A set of programs that facilitates rapid workflows to automate molecular dynamics calculations, from the setup processes to the analysis of trajectories. MoDEL: A database that holds simulations of more than 1700 proteins on the basis of their properties, dynamics and trajectories. ChemistriX: A virtual compound library with the purpose of complementing the chemistry available in current catalogues. It represents a novel pool of chemistry with which to carry out virtual screening. Our shareholders include the Botín Foundation (capital investor), the Barcelona Supercomputing Center (BSC), the Institute for Research in Biomedicine (IRB Barcelona), the University of Barcelona (UB), the Catalan Institute for Research and Advanced Studies (ICREA).
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