Insights

Strategic Acquisition Orna Therapeutics is a wholly owned subsidiary of Eli Lilly with strong strategic value as a platform for RNA therapeutics and in vivo cell therapy, making it a prime target for licensing, collaboration, or acquisition discussions to accelerate broader platform adoption.

Broad Pipeline The company is advancing circular RNA (oRNA) and LNP delivery platforms and in vivo CAR programs targeting autoimmune and oncology indications, presenting multiple cross-indication collaboration opportunities from autoimmune diseases to hematologic cancers.

In Vivo Focus Emphasis on in vivo cell therapy and RNA delivery suggests ripe opportunities for partners with complementary delivery technologies, manufacturing capabilities, or regional development expertise to co-develop or co-commercialize therapies.

Strategic Partnerships Past and ongoing collaborations in China (Greater China region) and with Shanghai Simnova indicate a willingness to form regional alliances, enabling BD leads to propose co-development, technology licenses, or market-entry agreements in key geographies.

Commercial Readiness Revenue range and substantial funding, plus a Linked strategic exit event mentioned by Lilly, imply appetite for scalable partnerships, milestone-driven deals, and potential license-out or co-commercialization structures to monetize the platform quickly.

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Orna Therapeutics Tech Stack

Orna Therapeutics uses 8 technology products and services including NetSuite, Shopify, Mimecast, and more. Explore Orna Therapeutics's tech stack below.

Media & News

Orna Therapeutics's Email Address Formats

Orna Therapeutics uses at least 3 email formats:
Orna Therapeutics Email FormatsExamplePercentage
FLast@ornatx.comJDoe@ornatx.com
89%
First.Last@ornatx.comJohn.Doe@ornatx.com
10%
FL@ornatx.comJD@ornatx.com
1%

Frequently Asked Questions

What is Orna Therapeutics's official website and social media links?

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Orna Therapeutics's official website is ornatx.com and has social profiles on LinkedIn and Crunchbase.

How much revenue does Orna Therapeutics generate?

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As of August 2026, Orna Therapeutics's annual revenue is estimated to be $50M - $100M.

What is Orna Therapeutics's SIC code and NAICS code?

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Orna Therapeutics's SIC code is 8731 - Commercial Physical and Biological Research and NAICS code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology).

How many employees does Orna Therapeutics have currently?

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As of August 2026, Orna Therapeutics has approximately 113 employees across 4 continents, including North America, Europe and Africa. Key team members include Ceo: S. D., Business Development Founder & Director: R. S. and Preclinical Research Co-Op: M. A. M. Explore Orna Therapeutics's employee directory with LeadIQ.

What industry does Orna Therapeutics belong to?

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Orna Therapeutics operates in the Biotechnology Research industry.

What technology does Orna Therapeutics use?

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Orna Therapeutics's tech stack includes NetSuite, Shopify, Mimecast, Google Cloud, DocuSign, Office 365, WP Engine and Smartsheet.

What is Orna Therapeutics's email format?

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Orna Therapeutics's email format typically follows the pattern of FLast@ornatx.com. Find more Orna Therapeutics email formats with LeadIQ.

How much funding has Orna Therapeutics raised to date?

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As of August 2026, Orna Therapeutics has raised $321M in funding. The last funding round occurred on Aug 16, 2022 for $221M.

When was Orna Therapeutics founded?

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Orna Therapeutics was founded in 2019.
Orna Therapeutics logo

Orna Therapeutics

Biotechnology ResearchMassachusetts, United States51-200 Employees

Orna Therapeutics is a mid-sized biotechnology company based in Watertown, Massachusetts. It is advancing RNA-based therapies by developing a circular RNA platform, known as oRNA, alongside new lipid nanoparticle delivery approaches to enable in vivo treatments for disease. The aim is to broaden the therapeutic potential of circular RNA and to support the development of safe, effective in vivo therapies.

In late 2025, the company reported preclinical data for its in vivo CAR programs targeting B cell–driven autoimmune diseases and BCMA-related conditions, presented at the ASH annual meeting. More recently, Orna disclosed the development of ORN-252, a program directed at the CD19 lymphocyte surface antigen for treating autoimmune diseases driven by B cells. These developments illustrate a concentrated effort on autoimmune indications and immune-cell–targeted approaches within its research portfolio.

Section iconCompany Overview

Website
ornatx.com
SIC Code
8731 - Commercial Physical and Biological Research
NAICS Code
541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Founded
2019
Employees
51-200

Section iconFunding & Financials

  • $321M

    Orna Therapeutics has raised a total of $321M of funding over 3 rounds. Their latest funding round was raised on Aug 16, 2022 in the amount of $221M as a Series B.

  • $50M - $100M

    Orna Therapeutics's revenue is estimated to be in the range of $50M - $100M

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