SilcsBio Employee Directory
Pharmaceutical ManufacturingMaryland, United States2-10 Employees
SilcsBio is a Baltimore, Maryland-based company in the pharmaceutical manufacturing industry that develops software and services for structure-based drug design. Its product portfolio includes SILCS, which maps chemical functional groups on proteins to provide 3-D maps and data to inform ligand design; Single Step FEP, a fast free-energy perturbation tool; and CGenFF, the CHARMM General Force Field program for parameterizing drug-like molecules. The tools support activities such as database screening, ligand optimization, fragment-based ligand design, and pharmacophore generation. The company released a CGenFF Web App in 2024 and followed with another web app release in 2025. The company employs a small team of 2 to 10 people and is based at 1100 Wicomico Street, Baltimore, MD, with a website at silcsbio.com.
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