Insights

Strategic IP leverage TRS possesses a strong IP position with an extensive patent portfolio and trade secrets around 3D printed resorbable scaffolds and the Affinity coating, suggesting opportunities to engage with OEMs and large implant manufacturers seeking differentiated coatings and scaffolds.

FDA cleared assets Both the 3D printed resorbable scaffold and the Affinity coating have FDA 510(k) clearance, enabling near-term discussions with medical device companies for licensing, co-development, or acquisition of commercial-ready tech.

Manufacturing readiness TRS operates an independent FDA-compliant manufacturing facility with a certified cleanroom capable of scaling to commercial volumes, making it feasible to partner on high-volume production or contract manufacturing for partner devices.

Clinical and research validation Extensive university, NIH, and company-sponsored research over a decade underpins the platform, providing a credible foundation for partnerships with academic centers, hospitals, and biotech firms pursuing regenerative solutions.

Acquisition and asset opportunity Past sale of 3D printing assets to DePuy Synthes signals a potential openness to collaboration or sale/partial license of technology or manufacturing capabilities with established medical device players seeking accelerated time-to-market.

Similar companies to Tissue Regeneration Systems, Inc.

Tissue Regeneration Systems, Inc. Tech Stack

Tissue Regeneration Systems, Inc. uses 8 technology products and services including Clicky, Cloudflare Web Optimizations, Cloudflare, and more. Explore Tissue Regeneration Systems, Inc.'s tech stack below.

  • Clicky
    Analytics
  • Cloudflare Web Optimizations
    Analytics
  • Cloudflare
    Content Management System
  • Content Management System
  • Cloudflare DNS
    Domain Name Services
  • MooTools
    Javascript Frameworks
  • jQuery
    Javascript Libraries
  • HTTP/3
    Web & Portal Technology

Tissue Regeneration Systems, Inc.'s Email Address Formats

Tissue Regeneration Systems, Inc. uses at least 2 email formats:
Tissue Regeneration Systems, Inc. Email FormatsExamplePercentage
First@tissuesys.comJohn@tissuesys.com
67%
First.Last@tissuesys.comJohn.Doe@tissuesys.com
33%

Frequently Asked Questions

What is Tissue Regeneration Systems, Inc.'s phone number?

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You can contact Tissue Regeneration Systems, Inc.'s main corporate office by phone at . For more prospecting data, LeadIQ has access to up-to-date and accurate contact information within our platform. Find, capture, and sync contact data to your CRM and sales tools in one click.

What is Tissue Regeneration Systems, Inc.'s official website and social media links?

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Tissue Regeneration Systems, Inc.'s official website is tissuesys.com and has social profiles on LinkedIn and Crunchbase.

How much revenue does Tissue Regeneration Systems, Inc. generate?

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As of August 2026, Tissue Regeneration Systems, Inc.'s annual revenue is estimated to be <$1M.

What is Tissue Regeneration Systems, Inc.'s SIC code and NAICS code?

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Tissue Regeneration Systems, Inc.'s SIC code is 8731 - Commercial Physical and Biological Research and NAICS code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology).

How many employees does Tissue Regeneration Systems, Inc. have currently?

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As of August 2026, Tissue Regeneration Systems, Inc. has approximately 3 employees across 1 continents, including North America. Key team members include Chairman: J. A. Explore Tissue Regeneration Systems, Inc.'s employee directory with LeadIQ.

What industry does Tissue Regeneration Systems, Inc. belong to?

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Tissue Regeneration Systems, Inc. operates in the Biotechnology Research industry.

What technology does Tissue Regeneration Systems, Inc. use?

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Tissue Regeneration Systems, Inc.'s tech stack includes Clicky, Cloudflare Web Optimizations, Cloudflare, Joomla, Cloudflare DNS, MooTools, jQuery and HTTP/3.

What is Tissue Regeneration Systems, Inc.'s email format?

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Tissue Regeneration Systems, Inc.'s email format typically follows the pattern of First@tissuesys.com. Find more Tissue Regeneration Systems, Inc. email formats with LeadIQ.

How much funding has Tissue Regeneration Systems, Inc. raised to date?

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As of August 2026, Tissue Regeneration Systems, Inc. has raised $18M in funding. The last funding round occurred on Jun 19, 2015 for $4.1M.
Tissue Regeneration Systems, Inc. logo

Tissue Regeneration Systems, Inc.

Biotechnology ResearchMichigan, United States2-10 Employees

Tissue Regeneration Systems is a small medical device startup based in Plymouth, Michigan, focused on skeletal reconstruction and bone regeneration through a technology platform licensed from the Universities of Michigan and Wisconsin. It can fabricate complex, patient-specific, load-bearing resorbable implants using 3D printing and complements them with a proprietary mineral coating that can also be applied to conventional orthopedic and spine implants.

The coating, named Affinity, mimics the mineral structure of native bone and modulates the surrounding biological environment. The company operates an independent, FDA-compliant manufacturing facility with a certified cleanroom and holds FDA 510(k) clearance for both its 3D-printed scaffolds and its Affinity coating. It maintains an extensive IP portfolio, including patents and trade secrets, supporting its position within the orthopedic and spine implant market as part of its biotechnology research focus.

Section iconCompany Overview

Phone number
SIC Code
8731 - Commercial Physical and Biological Research
NAICS Code
541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Employees
2-10

Section iconFunding & Financials

  • $18M

    Tissue Regeneration Systems, Inc. has raised a total of $18M of funding over 5 rounds. Their latest funding round was raised on Jun 19, 2015 in the amount of $4.1M as a Venture Round.

  • <$1M

    Tissue Regeneration Systems, Inc.'s revenue is estimated to be in the range of <$1M

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