Insights

Expanding Healthcare Focus Upstream Bio's strong progress in developing innovative treatments for inflammatory respiratory diseases, including severe asthma and nasal polyps, presents significant sales opportunities within the pharmaceutical and healthcare sectors looking for next-generation therapeutics.

Robust Financial Position With a current cash reserve of over $341 million expected to fund operations through 2027, Upstream Bio is positioned for continued clinical development and potential commercialization, creating opportunities to partner on early access and licensing of promising clinical-stage assets.

Strategic Clinical Advances The successful Phase 2 data and upcoming Phase 3 plans for verekitug, a novel agonist targeting inflammatory biomarkers, suggest potential for long-term sales growth, especially if the company gains regulatory approval in multiple indications across respiratory diseases.

Innovative Asset Pipeline Upstream Bio's focus on precision immunology with targeted biologics aligns well with market trends toward personalized medicine, offering opportunities for collaborations or sales of specialized therapeutic solutions to biotech firms and healthcare providers aiming to address complex inflammatory conditions.

Market Expansion Potential Given the company's international clinical trials and plans to initiate global Phase 3 trials, there are multiple opportunities for regional partners and distributors to engage early, facilitating market entry and accelerating the adoption of new therapies across diverse geographic regions.

Upstream Tech Stack

Upstream uses 8 technology products and services including Adobe, Google Cloud Platform, VMware vCenter, and more. Explore Upstream's tech stack below.

  • Adobe
    Audio, Video, Graphics
  • Google Cloud Platform
    Infrastructure As A Service
  • VMware vCenter
    IT Infrastructure & Operations Management
  • Fortinet
    Network Hardware
  • Cisco ASA
    Network Security
  • WP Engine
    Platform As A Service
  • Microsoft IIS
    Web Servers
  • Nginx
    Web Servers

Media & News

Upstream's Email Address Formats

Upstream uses at least 1 format(s):
Upstream Email FormatsExamplePercentage
First.Last@upstreamsystems.comJohn.Doe@upstreamsystems.com
89%
Last@upstreamsystems.comDoe@upstreamsystems.com
8%
FL@upstreamsystems.comJD@upstreamsystems.com
2%
First.Middle@upstreamsystems.comJohn.Michael@upstreamsystems.com
1%

Frequently Asked Questions

Where is Upstream's headquarters located?

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Upstream's main headquarters is located at Berkeley Square Office 286a 2nd Floor London, England United Kingdom. The company has employees across 6 continents, including EuropeNorth AmericaAfrica.

What is Upstream's phone number?

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You can contact Upstream's main corporate office by phone at . For more prospecting data, LeadIQ has access to up-to-date and accurate contact information within our platform. Find, capture, and sync contact data to your CRM and sales tools in one click.

What is Upstream's stock symbol?

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Upstream is a publicly traded company; the company's stock symbol is UPB.

What is Upstream's official website and social media links?

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Upstream's official website is upstreamsystems.com and has social profiles on LinkedInCrunchbase.

What is Upstream's NAICS code?

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Upstream's NAICS code is 5112 - Software Publishers.

How many employees does Upstream have currently?

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As of May 2026, Upstream has approximately 393 employees across 6 continents, including EuropeNorth AmericaAfrica. Key team members include Chief Executive Officer: D. M.Chief Executive Officer: A. V.Chief Practice Officer: N. H.. Explore Upstream's employee directory with LeadIQ.

What industry does Upstream belong to?

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Upstream operates in the Software Development industry.

What technology does Upstream use?

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Upstream's tech stack includes AdobeGoogle Cloud PlatformVMware vCenterFortinetCisco ASAWP EngineMicrosoft IISNginx.

What is Upstream's email format?

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Upstream's email format typically follows the pattern of First.Last@upstreamsystems.com. Find more Upstream email formats with LeadIQ.

How much funding has Upstream raised to date?

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As of May 2026, Upstream has raised $15M in funding. The last funding round occurred on Dec 19, 2022 for $15M.

When was Upstream founded?

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Upstream was founded in 2001.

Upstream

Software DevelopmentEngland, United Kingdom201-500 Employees

We are a leader in mobile technology, providing innovative solutions to 1.2 billion consumers. In an ever-increasing digital world we help businesses grow their digital reach & toolkits to optimize user experience, increase engagement, attract new customers and boost their revenues.

Think of performance marketing but on steroids as our top-notch marketeers and engineers build digital journeys through an omnichannel marketing approach like no other. Currently we work with the biggest names in Telco, Insurance, Education, FMCGs and Retail in over 45 countries in Latin America, Africa, the Middle East and South-East Asia.

Section iconCompany Overview

Headquarters
Berkeley Square Office 286a 2nd Floor London, England United Kingdom
Phone number
Stock Symbol
UPB
NAICS Code
5112 - Software Publishers
Founded
2001
Employees
201-500

Section iconFunding & Financials

  • $15M

    Upstream has raised a total of $15M of funding over 5 rounds. Their latest funding round was raised on Dec 19, 2022 in the amount of $15M.

  • $100M$250M

    Upstream's revenue is estimated to be in the range of $100M$250M

Section iconFunding & Financials

  • $15M

    Upstream has raised a total of $15M of funding over 5 rounds. Their latest funding round was raised on Dec 19, 2022 in the amount of $15M.

  • $100M$250M

    Upstream's revenue is estimated to be in the range of $100M$250M

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