Curis
Biotechnology ResearchMassachusetts, United States51-200 Employees
Curis is a publicly traded biotechnology company based in Lexington, Massachusetts, focused on developing first-in-class cancer therapeutics. It has drug candidates in development, including Emavusertib (CA-4948), an oral IRAK4 kinase inhibitor in Phase 1 trials for non-Hodgkin's lymphoma and for AML/MDS; and Fimepinostat, an oral HDAC/PI3K inhibitor under evaluation for future studies. Curis collaborates with Aurigene for discovery and development in immuno-oncology and precision oncology, and holds exclusive licenses to oral PD1/TIM3 dual antagonists such as CA-327 as well as IRAK4 inhibitors like CA-4948. Roche and Genentech, as collaborators, are commercializing Erivedge (vismodegib) for advanced basal cell carcinoma. In May 2026 Curis released its first-quarter 2026 business update.