DefenAge
Personal Care Product ManufacturingCalifornia, United States11-50 Employees
DefenAge develops skincare centered on its proprietary active ingredient, Age-Repair Defensins, a defensin-based component described as working through a natural mechanism. The core regimen was evaluated in a clinical study conducted at multiple centers with participants randomly assigned and assessed under blinded conditions, involving 44 individuals, and it reported improvements in visible signs of aging. Outcomes were assessed using histopathology and high-resolution skin ultrasound, and the regimen is designed to be compatible with many other regimens while remaining proprietary to DefenAge. Based in Carlsbad, California, DefenAge operates as a small-to-mid-sized player in the personal care product manufacturing sector. Its products target consumers seeking anti-aging skincare solutions, including those concerned with inflammation-related aging. In 2026, DefenAge's 7X Calming Complex was recognized as Best Inflammaging Serum at the NewBeauty Beauty Awards.