Guanine Inc

Biotechnology ResearchNew York, United States2-10 Employees

Guanine Inc is a biotechnology research company based in Rensselaer, New York. It is developing a universal electrochemical sensing platform that seeks to replace fragmented diagnostic methods with a single, scalable system capable of high-plex, multi-omic measurement from a single sample. The technology operates without optics, thermal cycling, or complex instrumentation, enabling rapid and cost-effective quantification of proteins, metabolites, nucleic acids, and functional drug responses, with plans to scale from point-of-care and hospital settings to OEM and high-throughput laboratory formats.

The company's initial clinical focus is sepsis, with a workflow under development that aims to deliver host response profiling in about 20 minutes, pathogen identification and antimicrobial resistance detection in about 60 minutes, and culture-free phenotyping in about 90 minutes. Guanine leverages deep electrochemical biosensing expertise and has a collaboration with Mount Sinai Health Systems, while actively engaging clinical partners and OEMs to scale the platform globally. OEM partners can deploy the platform to accelerate assay development, reduce system cost and complexity, and broaden multiplexing across infectious disease, chronic diseases, pharmaceutical diagnostics, and precision health AI applications.

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