Molecular Targeting Technologies,Inc

Pharmaceutical ManufacturingPennsylvania, United States2-10 Employees

A clinical stage business, developing theranostics for rare cancers.  

A Centocor spinoff, we’re rooted in a decade  of innovative collaborative research, a robust pipeline and an outstanding scientific network. 

In clinical development:

EBTATE (177Lu-EBTATE)  A long lived radiotherapeutic for gastroenteropancreatic neuroendocrine and Hürthle cell thyroid tumors (under license from the NIH)  Early human testing showed EBTATE is safe and more effective than competitors.  US trials begin in Q4 2021 at Memorial Sloan Kettering Cancer Center.

EBRGD (177Lu-EBRGD) A long-lived radiotherapeutic for αvβ3 expressing tumors.  We're targeting glioblastoma multiforme and non-small cell lung cancer. (under license from the NIH).  Trials planned in 2022.

FGA (18F-fluoroglucaric acid) A PET radiodiagnostic targeting histones released during necrosis and cell death.   Focused on tumor response to chemotherapy of brain and lung cancers.

TDURA (99mTc-duramycin) A SPECT radiodiagnostic targeting phosphatidylethanolamine, exposed on cell surfaces during cell death.   Focused on very early visualization of tumor death during chemotherapy, distinguishing responders from non-responders in one day. Phase 0/I trials in colorectal tumor response to therapy underway at the University of Antwerp.

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