Orionis Biosciences
Biotechnology ResearchMassachusetts, United States51-200 Employees
Orionis Biosciences is a mid-sized biotechnology research firm based in Waltham, Massachusetts, focused on genome-scale drug discovery and programmable design of therapeutic modalities. Its portfolio includes proprietary A-Kine biologics and Allo-Glue small-molecule platforms, designed to reprogram disease states and enable targeted immunotherapies. The company is actively advancing cancer immunotherapies and broader applications beyond oncology, reflecting its emphasis on precision, tunable therapeutics. In June 2026, Orionis announced a strategic collaboration with Novartis to discover and develop molecular glue medicines across multiple therapeutic areas. Positioned within the Massachusetts biotechnology ecosystem, the company collaborates with large pharma to advance novel modalities for cancer and other diseases.