Insights

Clinical momentum Early clinical-stage focus on verekitug, a TSLP receptor antagonist, signaling ongoing trials and potential expansion into additional inflammatory indications. This presents opportunities for CROs, clinical research services, and patient recruitment partners to support trial execution and data analysis.

Strategic partnerships Frequent conference participation and data sharing on Phase 2 VIBRANT trial indicate openness to collaboration. Potential sales opportunities exist with biotech service providers, contract manufacturing organizations, and platform collaborators that can accelerate development or expand manufacturing capabilities.

Healthcare visibility Active engagement with major investor and industry events (Goldman Sachs conference, EAACI, ATS, AAAAI) suggests a willingness to meet healthcare partners, payers, and researchers. This creates lead opportunities for advisory, market access consulting, and payer evidence generation services.

Financial runway Significant funding raised and a sizable revenue range imply budget for collaboration and outsourcing. Target strategic outsourcing proposals around early-phase studies, biomarker analytics, and regulatory support to maximize clinical development efficiency.

Scientific leadership Focus on upstream inflammatory signaling with a unique mechanism of action positions the company as a prime candidate for expert consulting, synthetic biology tooling, and specialized assay development partnerships to accelerate understanding of TSLP-driven pathways.

Upstream Bio Tech Stack

Upstream Bio uses 8 technology products and services including Squarespace, WordPress, Microsoft 365, and more. Explore Upstream Bio's tech stack below.

Media & News

Upstream Bio's Email Address Formats

Upstream Bio uses at least 1 format(s):
Upstream Bio Email FormatsExamplePercentage
First.Last@upstreambio.comJohn.Doe@upstreambio.com
100%

Frequently Asked Questions

What is Upstream Bio's stock symbol?

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Upstream Bio is a publicly traded company; the company's stock symbol is UPB.

What is Upstream Bio's official website and social media links?

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Upstream Bio's official website is upstreambio.com and has social profiles on LinkedInCrunchbase.

How much revenue does Upstream Bio generate?

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As of August 2026, Upstream Bio's annual revenue is estimated to be $25M - $50M.

What is Upstream Bio's SIC code NAICS code?

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Upstream Bio's SIC code is 8731 - Commercial Physical and Biological Research NAICS code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology).

How many employees does Upstream Bio have currently?

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As of August 2026, Upstream Bio has approximately 82 employees across 3 continents, including North AmericaEuropeSouth America. Key team members include Senior Vice President: C. N.Director, Clinical Operations: S. C.Senior Medical Director, Clinical Development: J. L.. Explore Upstream Bio's employee directory with LeadIQ.

What industry does Upstream Bio belong to?

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Upstream Bio operates in the Biotechnology Research industry.

What technology does Upstream Bio use?

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Upstream Bio's tech stack includes SquarespaceWordPressMicrosoft 365Jamf ProConstant ContactDocuSignWP EngineSmartsheet.

What is Upstream Bio's email format?

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Upstream Bio's email format typically follows the pattern of First.Last@upstreambio.com. Find more Upstream Bio email formats with LeadIQ.

How much funding has Upstream Bio raised to date?

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As of August 2026, Upstream Bio has raised $701M in funding. The last funding round occurred on Oct 10, 2024 for $200M.

When was Upstream Bio founded?

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Upstream Bio was founded in 2021.
Upstream Bio logo

Upstream Bio

Biotechnology ResearchMassachusetts, United States51-200 Employees

Upstream Bio is a mid-sized biotechnology research company based in Waltham, Massachusetts. It is advancing verekitug, a clinical-stage monoclonal antibody that targets the receptor for thymic stromal lymphopoietin, an upstream driver of inflammatory signaling. The company aims to improve treatment options for millions of patients living with severe inflammatory diseases, with an initial focus on severe respiratory disorders. Operating in the biotechnology sector, it seeks to address immune-mediated conditions through upstream modulation of inflammation. In June 2026, the company announced its participation in the Goldman Sachs Global Healthcare Conference, highlighting continued engagement with the scientific and investment communities.

Section iconCompany Overview

SIC Code
8731 - Commercial Physical and Biological Research
Stock Symbol
UPB
NAICS Code
541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Founded
2021
Employees
51-200

Section iconFunding & Financials

  • $701M

    Upstream Bio has raised a total of $701M of funding over 5 rounds. Their latest funding round was raised on Oct 10, 2024 in the amount of $200Mas a series_b.

  • $25M - $50M

    Upstream Bio's revenue is estimated to be in the range of $25M - $50M

Section iconFunding & Financials

  • $701M

    Upstream Bio has raised a total of $701M of funding over 5 rounds. Their latest funding round was raised on Oct 10, 2024 in the amount of $200Mas a series_b.

  • $25M - $50M

    Upstream Bio's revenue is estimated to be in the range of $25M - $50M

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