Insights

Innovative Clinical Pipeline Upstream's strong focus on advancing Phase 3 trials for verekitug indicates significant opportunities to collaborate or support in clinical development, regulatory pathways, and medical communications, targeting specialists in severe asthma and CRSwNP markets.

Robust Financial Position With a cash reserve of 341.5 million dollars expected to fund operations through 2027, the company is well-positioned to expand its clinical activities, potentially seeking strategic partnerships, licensing deals, or service providers to accelerate growth.

Therapeutic Efficacy Data Positive trial results demonstrating significant improvements in lung function and nasal symptoms suggest strong clinical validation that could be leveraged to engage healthcare providers and payers, highlighting the company's commitment to evidence-based care.

Market Expansion Potential Upstream’s focus on severe respiratory and inflammatory diseases positions it for growth across multiple specialty markets, creating opportunities for sales teams to target pulmonologists, allergists, and ENT specialists with tailored solutions or partnerships.

Engagement and Visibility Participation in upcoming investor conferences and presentation of late-breaking trial data reflect a proactive approach to raising awareness, which can be tapped into for inbound business prospects, collaborations, and awareness campaigns in the healthcare ecosystem.

UpStream Tech Stack

UpStream uses 8 technology products and services including SciPy, GitHub, Unpkg, and more. Explore UpStream's tech stack below.

  • SciPy
    Advanced Analytics And Data Science
  • GitHub
    Communication And Collaboration
  • Unpkg
    Content Delivery Network
  • Salesforce
    Customer Relationship Management
  • iOS
    Programming Languages
  • Lua
    Programming Languages
  • Python
    Programming Languages
  • OpenResty
    Web Servers

Media & News

UpStream's Email Address Formats

UpStream uses at least 1 format(s):
UpStream Email FormatsExamplePercentage
First.Last@upstream.careJohn.Doe@upstream.care
49%
Last@upstream.careDoe@upstream.care
1%
First.Last@upstream.careJohn.Doe@upstream.care
49%
Last@upstream.careDoe@upstream.care
1%

Frequently Asked Questions

Where is UpStream's headquarters located?

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UpStream's main headquarters is located at 1100 Revolution Mills Drive Suite 10 Greensboro, North Carolina 27405 United States. The company has employees across 1 continents, including North America.

What is UpStream's stock symbol?

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UpStream is a publicly traded company; the company's stock symbol is UPB.

What is UpStream's official website and social media links?

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UpStream's official website is upstream.care and has social profiles on LinkedInCrunchbase.

What is UpStream's NAICS code?

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UpStream's NAICS code is 62 - Health Care and Social Assistance.

How many employees does UpStream have currently?

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As of February 2026, UpStream has approximately 201 employees across 1 continents, including North America. Key team members include Chief Network Officer: A. S.Vice President Of Clinical Performance, Training And Education: M. B.Head Of Product Design: Z. S.. Explore UpStream's employee directory with LeadIQ.

What industry does UpStream belong to?

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UpStream operates in the Hospitals and Health Care industry.

What technology does UpStream use?

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UpStream's tech stack includes SciPyGitHubUnpkgSalesforceiOSLuaPythonOpenResty.

What is UpStream's email format?

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UpStream's email format typically follows the pattern of First.Last@upstream.care. Find more UpStream email formats with LeadIQ.

How much funding has UpStream raised to date?

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As of February 2026, UpStream has raised $140M in funding. The last funding round occurred on Dec 01, 2022 for $140M.

When was UpStream founded?

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UpStream was founded in 2018.

UpStream

Hospitals and Health CareNorth Carolina, United States201-500 Employees

At UpStream, we're dedicated to transforming primary care by focusing on preventative measures and enhancing the physician-patient relationship. Our innovative approach combines in-practice support with advanced technology and unique payment models to reduce avoidable suffering. Founded in 2018, our core values of independence, inclusion, and innovation guide us towards a more empowered, technology-integrated healthcare system. Our dynamic team is united by a shared passion for improving public health and making high-quality care accessible to all. Join us in our journey to redefine healthcare.

Section iconCompany Overview

Headquarters
1100 Revolution Mills Drive Suite 10 Greensboro, North Carolina 27405 United States
Stock Symbol
UPB
NAICS Code
62 - Health Care and Social Assistance
Founded
2018
Employees
201-500

Section iconFunding & Financials

  • $140M

    UpStream has raised a total of $140M of funding over 2 rounds. Their latest funding round was raised on Dec 01, 2022 in the amount of $140M.

  • $10M$25M

    UpStream's revenue is estimated to be in the range of $10M$25M

Section iconFunding & Financials

  • $140M

    UpStream has raised a total of $140M of funding over 2 rounds. Their latest funding round was raised on Dec 01, 2022 in the amount of $140M.

  • $10M$25M

    UpStream's revenue is estimated to be in the range of $10M$25M

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