Insights

Expanding Clinical Pipeline Upstream's recent successful Phase 2 trials for verekitug in treating severe respiratory disorders and nasal polyps indicate a strong pipeline of innovative therapies, creating opportunities to collaborate with healthcare providers and institutions seeking advanced treatment options.

Innovative Technology Deployment The company's utilization of advanced technological tools such as Salesforce, open-source platforms, and native mobile applications demonstrates a commitment to digital health solutions, positioning it well to partner with health systems and developers focused on tech integration and patient engagement.

Financial Growth Potential With substantial funding of $140 million and revenues between $10 million and $25 million, Upstream exhibits solid financial backing and growth potential, making it an attractive partner for investors and strategic alliances aiming to expand clinical reach and market access.

Market Focus on Respiratory Diseases Upstream's strategic focus on inflammatory and respiratory conditions like CRSwNP offers targeted sales opportunities with hospitals, clinics, and specialty care providers treating these complex disease areas, especially as innovative therapies move toward commercialization.

Thought Leadership & Industry Engagement Active participation in investor conferences and scientific forums indicates a proactive approach to industry influence and thought leadership, opening doors for partnership, co-marketing, and collaborative research initiatives with key stakeholders in healthcare and biotechnology sectors.

UpStream Tech Stack

UpStream uses 8 technology products and services including SciPy, GitHub, Unpkg, and more. Explore UpStream's tech stack below.

  • SciPy
    Advanced Analytics And Data Science
  • GitHub
    Communication And Collaboration
  • Unpkg
    Content Delivery Network
  • Salesforce
    Customer Relationship Management
  • iOS
    Programming Languages
  • Lua
    Programming Languages
  • Python
    Programming Languages
  • OpenResty
    Web Servers

Media & News

UpStream's Email Address Formats

UpStream uses at least 1 format(s):
UpStream Email FormatsExamplePercentage
First.Last@upstream.careJohn.Doe@upstream.care
49%
Last@upstream.careDoe@upstream.care
1%
First.Last@upstream.careJohn.Doe@upstream.care
49%
Last@upstream.careDoe@upstream.care
1%

Frequently Asked Questions

Where is UpStream's headquarters located?

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UpStream's main headquarters is located at 1100 Revolution Mills Drive, Suite 10 Greensboro, North Carolina 27405, NC. The company has employees across 1 continents, including North America.

What is UpStream's stock symbol?

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UpStream is a publicly traded company; the company's stock symbol is UPB.

What is UpStream's official website and social media links?

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UpStream's official website is upstream.care and has social profiles on LinkedInCrunchbase.

What is UpStream's NAICS code?

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UpStream's NAICS code is 62 - Health Care and Social Assistance.

How many employees does UpStream have currently?

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As of October 2025, UpStream has approximately 201 employees across 1 continents, including North America. Key team members include Chief Practice Officer: N. H.Chief Network Officer: A. S.Vice President Of Clinical Performance, Training And Education: M. B.. Explore UpStream's employee directory with LeadIQ.

What industry does UpStream belong to?

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UpStream operates in the Hospitals and Health Care industry.

What technology does UpStream use?

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UpStream's tech stack includes SciPyGitHubUnpkgSalesforceiOSLuaPythonOpenResty.

What is UpStream's email format?

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UpStream's email format typically follows the pattern of First.Last@upstream.care. Find more UpStream email formats with LeadIQ.

How much funding has UpStream raised to date?

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As of October 2025, UpStream has raised $140M in funding. The last funding round occurred on Dec 01, 2022 for $140M.

When was UpStream founded?

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UpStream was founded in 2018.
UpStream

UpStream

Hospitals and Health CareNew Caledonia201-500 Employees

At UpStream, we're dedicated to transforming primary care by focusing on preventative measures and enhancing the physician-patient relationship. Our innovative approach combines in-practice support with advanced technology and unique payment models to reduce avoidable suffering. Founded in 2018, our core values of independence, inclusion, and innovation guide us towards a more empowered, technology-integrated healthcare system. Our dynamic team is united by a shared passion for improving public health and making high-quality care accessible to all. Join us in our journey to redefine healthcare.

Section iconCompany Overview

Headquarters
1100 Revolution Mills Drive, Suite 10 Greensboro, North Carolina 27405, NC
Stock Symbol
UPB
NAICS Code
62 - Health Care and Social Assistance
Founded
2018
Employees
201-500

Section iconFunding & Financials

  • $140M

    UpStream has raised a total of $140M of funding over 2 rounds. Their latest funding round was raised on Dec 01, 2022 in the amount of $140M.

  • $10M$25M

    UpStream's revenue is estimated to be in the range of $10M$25M

Section iconFunding & Financials

  • $140M

    UpStream has raised a total of $140M of funding over 2 rounds. Their latest funding round was raised on Dec 01, 2022 in the amount of $140M.

  • $10M$25M

    UpStream's revenue is estimated to be in the range of $10M$25M

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