Isaac's Restaurants
RestaurantsPennsylvania, United States51-200 Employees
Isaac's Restaurants is a regional deli operator based in Lancaster, Pennsylvania, with thirteen locations across South Central Pennsylvania. The casual concept combines table service with takeout, online ordering, and catering, and it has expanded into a brewery format under the Isaac's Brewhouse brand. Its customer base includes local diners and event organizers seeking convenient, scalable dining and catering options within a single regional brand. The company operates in the restaurant industry as a multi-site operator, and recent actions in 2025 indicate a downsizing of its footprint, including the closure of one York County location and the dissolution of offices in South Carolina. Headquartered in Lancaster, the company maintains its footprint in the region as a mid-sized employer with operations focused on South Central Pennsylvania.