Replicate Bioscience, Inc.
Biotechnology ResearchCalifornia, United States11-50 Employees
Replicate Bioscience, Inc. operates in the biotechnology research space, pursuing RNA-based therapeutics through self-replicating RNA technology. Its srRNA constructs pair a replication-capable genetic payload with RNA that encodes a therapeutic protein, enabling controlled production of the target protein inside cells. The company maintains a library of synthetic srRNA vectors chosen to drive strong and sustained protein expression, with performance described as markedly better than traditional linear mRNA. These capabilities position Replicate to advance treatments in oncology, infectious disease, and autoimmunity, among other areas. Headquartered in San Diego, California, the company is described as a small-to-mid-sized biotechnology research firm with a focused team of srRNA experts. In 2025 and 2026, Replicate formed a multi-year collaboration with Novo Nordisk to develop srRNA-based therapies for obesity, Type 2 diabetes, and related cardiometabolic diseases, reflecting its position within the industry as a partner for large pharmaceutical developers.